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Article

Very Early Involvement of Innate Immunity in Peripheral Nerve Degeneration in SOD1-G93A Mice.

Frontiers in immunology - 1 Jan 2020

Angelini Daniela Francesca, De Angelis Federica, Vacca Valentina, Piras Eleonora, Parisi Chiara, Nutini Michele, Spalloni Alida, Pagano Francesca, Longone Patrizia, Battistini Luca, Pavone Flaminia, Marinelli Sara

Abstract excerpt

Recent preclinical and clinical evidence suggest that immune system has a role in the progression and prognosis of Amyotrophic Lateral Sclerosis (ALS), but the identification of a clear mechanism and immune players remains to be elucidated. Here, we have investigated, in 30 and 60 days (presymptomatic) and 120 days (symptomatic) old SOD1-G93A mice, systemic, peripheral, and central innate and adaptive immune and...

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Identifiers

PMID: 33329541
DOI: 10.3389/fimmu.2020.575792
PMCID: PMC7714949

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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