Article
Genetic risks and childhood-onset asthma.
The Journal of allergy and clinical immunology - 1 Aug 2011
Cookson William, Moffatt Miriam, Strachan David P
Abstract excerpt
Recent large-scale genome-wide association studies have successfully identified several genetic loci that influence asthma susceptibility. The loci thus far identified confer a high population attributable risk for childhood-onset disease and have provided a better understanding of the primary mechanisms underlying asthma and a clear focus for new therapies to treat the disease. The loci are of limited utility...
Topics
- Age of Onset
- Asthma
- Child
- Genetic Predisposition to Disease
- Genome, Human
- Genome-Wide Association Study
- Humans
- Risk Factors