Article

Aggregated <i>Mycobacterium tuberculosis</i> enhances the inflammatory response

2021-03-23

Abstract excerpt

Mycobacterium tuberculosis (Mtb) readily aggregates in culture and Mtb aggregates in the lung were observed in experimental Mtb infection. However, the physiological consequences of Mtb aggregation are incompletely understood. Here we examined the human macrophage transcriptional response to aggregated Mtb relative to infection with non-aggregated single or multiple bacilli per host cell. Infection with aggregated...

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Literature Corpus work: 14491bf9-d6f3-5735-9c98-09e4a3145182
DOI: 10.1101/2021.03.23.436577

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