Article

Impact of the elderly lung mucosa on <i>Mycobacterium tuberculosis</i> metabolic adaptation during infection of alveolar epithelial cells

2024-05-06

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Tuberculosis (TB) is one of the top leading causes of death due to a single infectious agent. Upon infection, Mycobacterium tuberculosis ( M.tb ) is deposited in the alveoli and encounters the lung mucosa or alveolar lining fluid (ALF). We previously determined that increased M.tb replication in human macrophages and alveolar epithelial cells (ATs) is mediated by age-asso...

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Literature Corpus work: 6f1f75ec-aad4-5771-a15e-98345472b81f
DOI: 10.1101/2024.05.06.592753

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