Article

Autophagy protects against high-dose <i>Mycobacterium tuberculosis</i> infection

2022-11-04

Abstract excerpt

<h4>Summary</h4> Host autophagy had been associated with the control of Mycobacterium tuberculosis (Mtb) infection due to its ability to sequesters microorganisms through a process termed “xenophagy” 1–4 . Xenophagy purportedly limits Mtb replication within infected macrophages 1–4 . However, studies in mice using a standard low-dose infection model demonstrated that xenophagy in infected phagocytes is not req...

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Literature Corpus work: 386968a3-96bb-58fd-a284-c8e3e6fe2590
DOI: 10.1101/2022.11.04.515158

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