Article
Host- and age-dependent transcriptional changes in <i>Mycobacterium tuberculosis</i> cell envelope biosynthesis genes after exposure to human alveolar lining fluid
2021-09-08
Abstract excerpt
Tuberculosis (TB) infection, caused by the airborne pathogen Mycobacterium tuberculosis ( M . tb ), resulted in almost 1.4 million deaths in 2019 and the number of deaths is predicted to increase by 20% over the next 5 years due to the COVID-19 pandemic. Upon reaching the alveolar space, M . tb comes in close contact with the lung mucosa before and after its encounter with host alveolar compartment cells. Our...
Topics
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- Antibiotic Resistance in Bacteria
- Diagnosis and treatment of tuberculosis
- Infectious Diseases and Tuberculosis
- Mycobacterium research and diagnosis
- Neonatal Respiratory Health Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Pneumonia and Respiratory Infections
- Tuberculosis Research and Epidemiology
Identifiers and source
- Literature Corpus work
- a2d2dae7-378e-5ff7-be3f-02787d983d5f
- DOI
- 10.1101/2021.09.08.459334
