Article

Bexarotene induces differentiation of myeloid-derived suppressor cells through Arg-1 signalling pathway

2023-06-13

Abstract excerpt

<h4>Background: </h4> Cellular therapy has emerged as a promising strategy to minimize conventional immunosuppressive drugs and ultimately induce long-term graft survival. Myeloid-derived suppressor cells (MDSCs) could be utilized for immunosuppressive treatment in solid organ transplant. <h4>Methods:</h4> In this study, granular macrophage colony-stimulating factor (GM-CSF) and Bexarotene, a retinoid X receptor-s...

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Literature Corpus work: 143aa10f-ffe9-5420-b872-4574011a9409
DOI: 10.22541/au.168661983.30058062/v1

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