Article
Jagged-2 enhances immunomodulatory activity in adipose derived mesenchymal stem cells.
Scientific reports - 28 Sept 2015
Xishan Zhu, Bin Zhang, Haiyue Zhao, Xiaowei Dou, Jingwen Bai, Guojun Zhang
Abstract excerpt
Adipose derived Mesenchymal stem cells (AMSCs) are able to expand in vitro and undergo differentiation into multiple cell lineages, yet have low immunogenicity while exhibiting several immunoregulatory characteristics. We sought to investigate the immunomodulatory mechanisms of AMSCs to better understand their immunogenic properties. Following 10 days of chondrogenic differentiation or 48 hours of IFN-γ...
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