Article
Differentiation and immunosuppressive function of CD19+CD24hiCD27+ regulatory B cells are regulated through the miR-29a-3p/NFAT5 pathway.
Hepatobiliary & pancreatic diseases international : HBPD INT - 1 Oct 2024
Li Jin-Yang, Feng Tian-Shuo, Gao Ji, Yang Xin-Xiang, Li Xiang-Cheng, Deng Zhen-Hua, Xia Yong-Xiang, Wu Zheng-Shan
Abstract excerpt
BACKGROUND: Regulatory B cells (Bregs) is an indispensable element in inducing immune tolerance after liver transplantation. As one of the microRNAs (miRNAs), miR-29a-3p also inhibits translation by degrading the target mRNA, and yet the relationship between Bregs and miR-29a-3p has not yet been fully explored. This study aimed to investigate the impact of miR-29a-3p on the regulation of differentiation and...
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