Article
Dexamethasone potentiates myeloid-derived suppressor cell function in prolonging allograft survival through nitric oxide.
Journal of leukocyte biology - 1 Nov 2014
Liao Jiongbo, Wang Xiao, Bi Yujing, Shen Bo, Shao Kun, Yang Hui, Lu Yun, Zhang Zhengguo, Chen Xi, Liu Huanrong, Wang Jian, Chu Yiwei, Xue Lixiang, Wang Xianghui, Liu Guangwei
Abstract excerpt
Whereas GCs have been demonstrated to be beneficial for transplantation patients, the pharmacological mechanisms remain unknown. Herein, the role of GR signaling was investigated via a pharmacological approach in a murine allogeneic skin transplantation model. The GC Dex, a representative GC, sig...
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