Article

A Germinal Center–Independent Innate-Like Memory B Cell Compartment of B1 Origin

2026-07-25

Abstract excerpt

<h4>ABSTRACT</h4> Memory B cells (MBCs) are a critical cellular reservoir for long-term humoral immunity. MBCs display heterogeneous isotypes and surface markers and can arise through both germinal center (GC)-dependent and GC-independent extrafollicular (EF) pathways. Both the mechanisms controlling EF MBC differentiation and the identities of the B cell populations from which EF MBCs derive remain poorly unders...

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Literature Corpus work: 141f6a84-3fdc-59da-96e7-31222f56fc46
DOI: 10.64898/2026.07.22.740083

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