Article
Germinal center-dependent and -independent memory B cells produced throughout the immune response.
The Journal of experimental medicine - 2 Aug 2021
Viant Charlotte, Wirthmiller Tobias, ElTanbouly Mohamed A, Chen Spencer T, Kara Ervin E, Cipolla Melissa, Ramos Victor, Oliveira Thiago Y, Stamatatos Leonidas, Nussenzweig Michel C
Abstract excerpt
Memory B cells comprise a heterogenous group of cells that differ in origin and phenotype. During the early phases of the immune response, activated B cells can differentiate into IgM-expressing memory cells, short-lived plasma cells, or seed germinal centers (GCs). The memory compartment is subsequently enriched by B cells that have been through several rounds of division and selection in the GC. Here, we report...
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