Article

Separable multidimensional MRI signatures of cellular and structural pathology in Alzheimer’s disease

2026-04-06

Abstract excerpt

Cognitive decline in Alzheimer’s disease (AD) reflects progressive disruption of cellular and microstructural organization, yet the biological specificity of MRI signals remains incompletely understood. Multidimensional diffusion–relaxation MRI (MD-MRI) resolves sub-voxel tissue heterogeneity, offering a potential framework to link imaging signals to underlying pathology. We tested the hypothesis that neuronal, gl...

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Literature Corpus work: 78897ec7-88fe-59c1-8cb3-d89ebee27e0b
DOI: 10.64898/2026.04.02.716156

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