Article

Multifaceted roles of cohesin in regulating transcriptional loops

2024-03-27

Abstract excerpt

Cohesin is required for chromatin loop formation. However, its precise role in regulating gene transcription remains largely unknown. We investigated the relationship between cohesin and RNA Polymerase II (RNAPII) using single-molecule mapping and live-cell imaging methods in human cells. Cohesin-mediated transcriptional loops were highly correlated with those of RNAPII and followed the direction of gene transcrip...

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Literature Corpus work: 13543e92-b34a-557d-95f0-651dfc8f9948
DOI: 10.1101/2024.03.25.586715

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