Article

Lesion-remote astrocytes govern microglia-mediated white matter repair

2024-03-17

Abstract excerpt

Spared regions of the damaged central nervous system undergo dynamic remodeling and exhibit a remarkable potential for therapeutic exploitation. Here, lesion-remote astrocytes (LRAs), which interact with viable neurons, glia and neural circuitry, undergo reactive transformations whose molecular and functional properties are poorly understood. Using multiple transcriptional profiling methods, we interrogated LRAs f...

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Literature Corpus work: 132675d6-99c9-519b-a959-f7e5a25e7f4a
DOI: 10.1101/2024.03.15.585251

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