Article

scVI- and RNA Velocity–Integrated Fate Dynamics Reveal Latent Stability Architecture Underlying Melanoma Therapy Resistance

2026-05-15

Abstract excerpt

<title>Abstract</title> <p>Melanoma therapy resistance remains a major clinical challenge because heterogeneous tumour cell populations can dynamically reorganize under treatment pressure and regenerate disease after initial response. Although single-cell transcriptomics and RNA velocity have improved characterization of transient cellular transitions, current approaches often fail to resolve how local transcript...

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Literature Corpus work: 1314e33d-27a9-54f0-bdee-94e7e3992d69
DOI: 10.21203/rs.3.rs-9709612/v1

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