Article

Model-based inference of RNA velocity modules improves cell fate prediction

2023-08-05

Abstract excerpt

RNA velocity is a powerful paradigm that exploits the temporal information contained in spliced and unspliced RNA counts to infer transcriptional dynamics. Existing velocity models either rely on coarse biophysical simplifications or require extensive numerical approximations to solve the underlying differential equations. This results in loss of accuracy in challenging settings, such as complex or weak transcript...

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Literature Corpus work: 6cd9c488-cb97-5a4d-88bd-8bfcff58e0ac
DOI: 10.1101/2023.08.03.551650

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