Article

The alternative NF-κB RelB subunit is a novel critical sensor of lipid metabolism to promote tumor development

2024-10-18

Abstract excerpt

<title>Abstract</title> <p>Cancer cells reprogram their metabolism to fulfill their high energetic demand. Lipid metabolism is most often reprogrammed for cancer cell survival and tumor development. The role of alternative oncogenic NF-κB/RelB subunit in the reprogramming of lipid metabolism in cancer is unknown. Here we report that RelB plays a central role at the crossroads of lipid storage and liberation of fa...

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Literature Corpus work: 12cc6cb6-233d-53a4-b21a-6a7ede5ef26a
DOI: 10.21203/rs.3.rs-5233947/v1

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