Article

RelB Upregulates PD-L1 and Exacerbates Prostate Cancer Immune Evasion

2021-09-08

Abstract excerpt

<title>Abstract</title> <p>Background Interaction between programmed death receptor (PD-1) and its ligand (PD-L1) is essential for suppressing activated T-lymphocytes. However, the precise mechanisms underlying PD-L1 overexpression in tumors remain to be fully elucidated. Here, we describe that RelB participates in immune evasion of prostate cancer (PCa) via <italic>cis/trans</italic> transcriptional upregulation...

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Literature Corpus work: 1ff51017-f2a5-5a01-bcdd-c7b1badf207a
DOI: 10.21203/rs.3.rs-861355/v1

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