Article

ERK signaling dissolves ERF Repression Condensates in Living Embryos

2021-10-01

Abstract excerpt

<h4>ABSTRACT</h4> Phase separation underlies the organization of the nucleus, including the biogenesis of nucleoli and the packaging of heterochromatin. Here we explore the regulation of transcription factor condensates involved in gene repression by ERK signaling in gastrulating embryos of a simple proto-vertebrate ( Ciona ). ERK signaling induces nuclear export of the transcriptional repressor ERF, which has b...

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Literature Corpus work: 12c47770-7fee-53d2-b1e6-dc77d9028fb7
DOI: 10.1101/2021.10.01.462829

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