Article

Biomolecular condensates of Eya drive transcriptional co-activation associated with eye development

2025-10-15

Abstract excerpt

Eyes absent (Eya), a transcriptional coactivator essential for eye development in Drosophila, also plays an important role in organ development in mammals and is associated with several diseases. To better understand the mechanism of Eya-mediated transcriptional co-activation, we find that Eya forms biomolecular condensates with liquid-like properties. These condensates function as possible transcription hubs, thr...

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Literature Corpus work: 1ddf198a-6ffa-5e93-9d3c-ba8b75bc7bee
DOI: 10.1101/2025.10.15.682020

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