Article

Condensin II collaborates with cohesin to establish and maintain interphase chromosome territories

2025-07-28

Abstract excerpt

Despite the well-established role of condensin II in mitotic chromosome assembly, its function in interphase chromosome organization remains poorly understood. Here, we applied multiscale fluorescence in situ hybridization (FISH) techniques to human cell lines engineered for single or double depletion of condensin II and cohesin, and examined their functional interplay at two distinct stages of the cell cycle. Our...

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Literature Corpus work: f7f57005-10a1-5942-a809-237735d1857c
DOI: 10.1101/2025.07.25.666893

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