Article

Regulation of gene expression by repression condensates during development

2020-03-04

Abstract excerpt

There is emerging evidence for transcription condensates in the activation of gene expression 1–3 . However, there is considerably less information regarding transcriptional repression, despite its pervasive importance in regulating gene expression in development and disease. Here, we explore the role of liquid-liquid phase separation (LLPS) in the organization of the Groucho/TLE (Gro) family of transcriptional c...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 07bd6046-169a-5109-90e7-f05196866354
DOI: 10.1101/2020.03.03.975680

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Regulation of gene expression by repression condensates during developmentDOI 10.1101/2020.03.03.975680Read

Dynamic compartmentalization of the pro-invasive transcription factor NHR-67 reveals a role for Groucho in regulating a proliferative-invasive cellular switch in C. elegansSemantic proximity Read

Trailer Hitch tunes condensate phase behavior and mRNA partitioning to regulate P-body homeostasis during <i>Drosophila melanogaster</i> oogenesisSemantic proximity Read

ERK signaling dissolves ERF Repression Condensates in Living EmbryosSemantic proximity Read

HERD-1 mediates multiphase condensate immiscibility to regulate small RNA-driven transgenerational epigenetic inheritance.Semantic proximity Read

Selective RNA sequestration in biomolecular condensates directs cell fate transitionsSemantic proximity Read

Phase separation of Arabidopsis EMB1579 controls transcription, mRNA splicing, and development.Semantic proximity Read

Merging Established Mechanisms with New Insights: Condensates, Hubs, and the Regulation of RNA Polymerase II Transcription.Semantic proximity Read

An architectural role of <i>oskar</i> mRNA in granule assemblySemantic proximity Read

Stonewalling Drosophila stem cell differentiation by epigenetic controls.Semantic proximity Read

RNA binding is essential for NONO condensates to modulate pre-mRNA processing of super enhancer-associated genes in neuroblastomaSemantic proximity Read

Characterization of factors that underlie transcriptional silencing in <i>C. elegans</i> oocytesSemantic proximity Read

Investigating the Context-Dependent Phase Separation of Human HOX Transcription FactorsSemantic proximity Read