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IdentifiHR: predicting homologous recombination deficiency in high-grade serous ovarian carcinoma using gene expression

2024-08-16

Abstract excerpt

<h4>Background</h4> Approximately half of all high-grade serous ovarian carcinomas (HGSCs) have a therapeutically targetable defect in the homologous recombination (HR) DNA repair mechanism. While there are genomic and transcriptomic methods, developed for other cancer types, to identify HR deficient (HRD) samples, there are no gene expression-based tools to predict HR repair status in HGSC specifically. We have...

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Literature Corpus work
1292fb70-8137-5f69-8aae-416a41c345b0
DOI
10.1101/2024.08.15.608185
Open publication

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IdentifiHR: predicting homologous recombination deficiency in high-grade serous ovarian carcinoma using gene expressionDOI 10.1101/2024.08.15.608185
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