Article

A transgenic mouse allows to capture the HLA-C*06:02 immunopeptidome in a model of psoriasis

2025-05-03

Abstract excerpt

Psoriasis vulgaris is a T cell-mediated autoimmune skin condition affecting around one in fifty people worldwide. Whilst advanced immunomodulatory therapeutic options have become available in recent years, ongoing disease suppression is still required with no curative treatment available to date. The human leukocyte antigen class I allele HLA-C*06:02 is the main genetic risk determinant of psoriasis. Its function...

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Literature Corpus work: 128d9680-b922-585b-acd2-1c6755e4b979
DOI: 10.1101/2025.05.01.651638

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