Article
The Human Immunopeptidome Project: A Roadmap to Predict and Treat Immune Diseases.
Molecular & cellular proteomics : MCP - 1 Jan 2020
Vizcaíno Juan Antonio, Kubiniok Peter, Kovalchik Kevin A, Ma Qing, Duquette Jérôme D, Mongrain Ian, Deutsch Eric W, Peters Bjoern, Sette Alessandro, Sirois Isabelle, Caron Etienne
Abstract excerpt
The science that investigates the ensembles of all peptides associated to human leukocyte antigen (HLA) molecules is termed "immunopeptidomics" and is typically driven by mass spectrometry (MS) technologies. Recent advances in MS technologies, neoantigen discovery and cancer immunotherapy have catalyzed the launch of the Human Immunopeptidome Project (HIPP) with the goal of providing a complete map of the human...
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