Article

Distinct myeloid precursors and their interaction with mesenchymal cells orchestrate the spreading of psoriatic disease from the skin to the joints

2025-08-15

Abstract excerpt

<h4>ABSTRACT</h4> Psoriatic disease initially affects the skin, but later extends to the joints. Herein, we describe a two-step process that orchestrates spreading of inflammation from the skin to the joints. Induction of psoriatic skin disease in photoconvertible mice, followed by sequencing and computational characterization of skin-derived cells in the joints, identified a unique population of CD2 + MHC-II +...

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Literature Corpus work: 62c26800-e219-51c5-9f6b-c222db915646
DOI: 10.1101/2025.08.14.665302

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