Article
Cross-sectional study reveals that HLA-C*07:02 is a potential biomarker of early onset/lesion severity of psoriasis.
Experimental dermatology - 1 Jul 2020
Li Junqin, Li Xiaofang, He Fusheng, Zhao Xincheng, Hou Ruixia, Lin Haoxiang, Shen Juan, Wu Xueli, Liao Qijun, Xing Jianxiao, Yin Guohua, Li Xinhua, Zhang Kaiming
Abstract excerpt
Psoriasis is a common chronic autoimmune skin disease, with T cells playing a predominant role in its pathogenesis. Here, we aimed to investigate the relation of T-cell repertoires (TCR) and major histocompatibility complex (MHC) in psoriatic patients to further understand mechanisms in disease pathogenesis. We conducted a cross-sectional study involving nine pairs of monozygotic twins with inconsistent psoriasis...
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