Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human Leukocyte Antigen-Class I Alleles and the Autoreactive T Cell Response in Psoriasis Pathogenesis.

Frontiers in immunology - 1 Jan 2018

Prinz Jörg Christoph

Abstract excerpt

Psoriasis is a complex immune-mediated inflammatory skin disease characterized by T-cell-driven epidermal hyperplasia. It occurs on a strong genetic predisposition. The human leukocyte antigen (HLA)-class I allele HLA-C*06:02 on psoriasis susceptibility locus 1 (PSORS1 on 6p21.3) is the main psoriasis risk gene. Other HLA-class I alleles encoding HLA molecules presenting overlapping peptide repertoires show...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoantigens
Share to Autoimmunity
Share to CD8-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epidermis

Share to Histocompatibility Antigens Class I

Share to Melanocytes

Share to Psoriasis

Source

Open in PubMed Open full text

Identifiers

PMID: 29760713
DOI: 10.3389/fimmu.2018.00954
PMCID: PMC5936982

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human Leukocyte Antigen-Class I Alleles and the Autoreactive T Cell Response in Psoriasis Pathogenesis.PMID 29760713Read ↗

Melanocyte antigen triggers autoimmunity in human psoriasisSemantic proximity Read ↗

The immunogenetics of Psoriasis: A comprehensive review.Semantic proximity Read ↗

Review: A Contemporary, Multifaced Insight into Psoriasis PathogenesisSemantic proximity Read ↗

Molecular Mechanisms and Management of a Cutaneous Inflammatory Disorder: Psoriasis.Semantic proximity Read ↗

Cross-sectional study reveals that HLA-C*07:02 is a potential biomarker of early onset/lesion severity of psoriasis.Semantic proximity Read ↗

Immunogenetics in psoriasis: towards personalised diagnosis and treatment strategies.Semantic proximity Read ↗

HLA DR B1*04, *07-restricted epitopes on Keratin 17 for autoreactive T cells in psoriasisSemantic proximity Read ↗

Psoriasis: An Immunogenetic PerspectiveSemantic proximity Read ↗

A Multifaced Approach on Psoriasis PathogenesisSemantic proximity Read ↗

[Pathogenesis of psoriasis].Semantic proximity Read ↗

Immunology of psoriasis.Semantic proximity Read ↗

Combining Understanding of Immunological Mechanisms and Genetic Variants Toward Development of Personalized Medicine for Psoriasis PatientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.