Article

Deciphering the tumor-specific immunopeptidome in vivo with genetically engineered mouse models

2021-07-12

Abstract excerpt

<title>Abstract</title> <p>Effective immunosurveillance of cancer requires the presentation of peptide antigens on major histocompatibility complex Class I (MHC-I). Recent developments in proteomics have improved the identification of peptides that are naturally presented by MHC-I, collectively known as the “immunopeptidome”. Current approaches to profile tumor immunopeptidomes have been limited to in vitro inves...

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Literature Corpus work: d2742a7e-ecae-50e0-ba3b-0bddda055723
DOI: 10.21203/rs.3.rs-669497/v1

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