Article

Characterizing higher order structures of chromatin in human cells

2018-02-19

Abstract excerpt

Packaging of DNA into chromatin regulates DNA accessibility and, consequently, all DNA-dependent processes, such as transcription, recombination, repair, and replication. The nucleosome is the basic packaging unit of DNA forming arrays that are suggested, by biochemical studies, to fold hierarchically into ordered higher-order structures of chromatin. This defined organization of chromatin has been recently questi...

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Literature Corpus work: 1262d9a8-485d-57de-b3d8-425388b4e1a0
DOI: 10.1101/267856

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