Article

Heterochromatin rewiring and domain disruption-mediated chromatin compaction during erythropoiesis

2021-08-12

Abstract excerpt

Development of mammalian red blood cells involves progressive chromatin compaction and subsequent enucleation in terminal stages of differentiation, but the molecular mechanisms underlying the three-dimensional chromatin reorganization and compaction remains obscure. Here, we systematically analyze the distinct features of higher-order chromatin in purified populations of primary human erythroblasts. Our results r...

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Literature Corpus work: e0c0619d-6a9a-5c54-b067-b2e9197706e0
DOI: 10.1101/2021.08.12.456090

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