Article
Chromatin structure and organization: the relation with gene expression during development and disease.
Sub-cellular biochemistry - 1 Jan 2013
Moindrot Benoît, Bouvet Philippe, Mongelard Fabien
Abstract excerpt
The elementary level of chromatin fiber, namely the nucleofilament, is known to undergo a hierarchical compaction leading to local chromatin loops, then chromatin domains and ultimately chromosome territories. These successive folding levels rely on the formation of chromatin loops ranging from few kb to some Mb. In addition to a packaging and structural role, the high-order organization of genomes functionally...
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