Article

Long-term motor and cognitive outcome of Deep Brain Stimulation in GBA-PD: the Italian PARKNET study

2024-12-28

Abstract excerpt

Deep brain stimulation (DBS) is an established therapeutic option for Parkinson Disease (PD), with demonstrated efficacy on motor symptoms also in patients carrying GBA1 variants (GBA-PD). However, it was recently suggested that DBS may accelerate cognitive decline in this frequent genetic subgroup, raising major concerns on its indication. Primary aim of this study was to investigate the possible additive effects...

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Literature Corpus work: 1240fab1-8eeb-585d-9789-b6c334729838
DOI: 10.1101/2024.12.23.24319546

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