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Article

Clinical Utility of GBA Genotyping Prior to Deep Brain Stimulation: A Narrative Review.

Genes - 6 Jan 2026

Rački Valentino, Lasić Slaven, Ðerke Filip, Belančić Andrej, Sošić Matija

Abstract excerpt

Background: Variants in the GBA gene represent the most common genetic risk factor for Parkinson's disease and are associated with a more aggressive disease course. Deep brain stimulation is an established therapy for advanced Parkinson's disease, yet the influence of GBA status on postoperative outcomes remains incompletely defined. This review aims to summarize the clinical relevance of GBA genotyping prior to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41595489
DOI: 10.3390/genes17010069
PMCID: PMC12840961

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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