Article

Contrasting determinants of mutation rates in germline and soma

2017-03-16

Abstract excerpt

Recent studies of somatic and germline mutations have led to the identification of a number of factors that influence point mutation rates, including CpG methylation, expression levels, replication timing and GC content. Intriguingly, some of the effects appear to differ between soma and germline: in particular, whereas mutation rates have been reported to decrease with expression levels in tumors, no clear effect...

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Literature Corpus work: 12012b91-3100-51c9-af75-f1c8032aaa5f
DOI: 10.1101/117325

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