Article

Contribution of TREM2 Signaling to the Development of Painful Diabetic Neuropathy by Mediating Microglial Polarization in Mice

2021-10-26

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Painful diabetic neuropathy (PDN) is a common and intractable complication of diabetes mellitus, with little effective treatment. PDN has been associated with spinal neuroinflammation characterized by microglial activation. Recently, the triggering receptor expressed on myeloid cells 2 (TREM2), specifically localized on microglia, has been identified as a vital...

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Literature Corpus work: 11856fa4-9bbd-541e-976c-ebe056e95b3a
DOI: 10.21203/rs.3.rs-671471/v2

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