Back to search

Article

The long non-coding RNA <i>H19</i> drives the proliferation of diffuse intrinsic pontine glioma with H3K27 mutation

2021-07-19

Abstract excerpt

<h4>ABSTRACT</h4> Diffuse intrinsic pontine glioma (DIPG) is an incurable paediatric malignancy. Identifying molecular drivers of DIPG progression is of utmost importance. Long non-coding RNAs (lncRNAs) represent a large family of disease- and tissue-specific transcripts, whose functions have not been yet elucidated in DIPG. Here, we study the oncogenic role of the development-associated H19 lncRNA in DIPG. Bioi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
11774c32-1053-5371-8e5f-703008fa7a9d
DOI
10.1101/2021.07.19.452516
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The long non-coding RNA <i>H19</i> drives the proliferation of diffuse intrinsic pontine glioma with H3K27 mutationDOI 10.1101/2021.07.19.452516
The Long Non-Coding RNA H19 Drives the Proliferation of Diffuse Intrinsic Pontine Glioma with H3K27 Mutation.Semantic proximity
Pediatric Diffuse Midline Glioma H3K27-Altered: From Developmental Origins to Therapeutic ChallengesSemantic proximity
Epigenetic reprogramming and chromatin accessibility in pediatric diffuse intrinsic pontine gliomas: a neural developmental disease.Semantic proximity
Oncohistones and disrupted development in pediatric-type diffuse high-grade glioma.Semantic proximity
Epigenomic landscape and 3D genome structure in pediatric high-grade glioma.Semantic proximity
Unique genetic and epigenetic mechanisms driving paediatric diffuse high-grade glioma.Semantic proximity
LncRNA H19: A novel oncogene in multiple cancersSemantic proximity
Targeting the SP/KLF Transcriptional Regulatory Network Synergizes with HDAC Inhibition to Impede Progression of H3K27M Diffuse Intrinsic Pontine Glioma.Semantic proximity
K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas.Semantic proximity
Oncohistone Mutations in Diffuse Intrinsic Pontine Glioma.Semantic proximity
Histone H3.3 K27M chromatin functions implicate a network of neurodevelopmental factors including ASCL1 and NEUROD1 in DIPG.Semantic proximity
Emerging Advances in Combinatorial Treatments of Epigenetically Altered Pediatric High-Grade H3K27M GliomasSemantic proximity
Select a neighboring publication to make it the new centre.