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Article

The Long Non-Coding RNA H19 Drives the Proliferation of Diffuse Intrinsic Pontine Glioma with H3K27 Mutation.

International journal of molecular sciences - 25 Aug 2021

Roig-Carles David, Jackson Holly, Loveson Katie F, Mackay Alan, Mather Rebecca L, Waters Ella, Manzo Massimiliano, Alborelli Ilaria, Golding Jon, Jones Chris, Fillmore Helen L, Crea Francesco

Abstract excerpt

Diffuse intrinsic pontine glioma (DIPG) is an incurable paediatric malignancy. Identifying the molecular drivers of DIPG progression is of the utmost importance. Long non-coding RNAs (lncRNAs) represent a large family of disease- and tissue-specific transcripts, whose functions have not yet been elucidated in DIPG. Herein, we studied the oncogenic role of the development-associated H19 lncRNA in DIPG....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34502082
DOI: 10.3390/ijms22179165
PMCID: PMC8431314

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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