Article
Possible association between TGF-β1 polymorphism and oral cancer.
International journal of immunogenetics - 1 Aug 2013
Carneiro N K, Oda J M M, Losi Guembarovski R, Ramos G, Oliveira B V, Cavalli I J, de S F Ribeiro E M, Gonçalves M S B, Watanabe M A E
Abstract excerpt
Oral squamous cell carcinoma (OSCC) is a worldwide health problem because it is a great cause of cancer morbidity and mortality. The transforming growth factor-β1 (TGF-β1) is involved in the regulation of numerous immunomodulatory processes. Thus, the aim of this case-control study was to investigate the possible association between the TGF-β1T869C polymorphism and oral cancer. The genomic DNA extracted from...
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