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Article

Novel mutations and expression alterations in SMAD3/TGFBR2 genes in oral carcinoma correlate with poor prognosis.

Genes, chromosomes & cancer - 1 Nov 2013

Sivadas Vadakke Peringode, George Nebu Abraham, Kattoor Jayasree, Kannan S

Abstract excerpt

Transforming growth factor beta (TGF-β) signaling is a pleiotropic cytokine signaling pathway, which controls cellular activities ranging from embryogenesis to apoptosis. Although many molecular alterations in this pathway have been described in cancers, the central point of concern, that is how these alterations influence the treatment outcome, has been addressed to a lesser extent. In this study, we have...

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Source

Identifiers

PMID: 23913824
DOI: 10.1002/gcc.22099

Genes

TGFBR2
SMAD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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