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Article

Expression and epigenomic landscape of the sex chromosomes in mouse post-meiotic male germ cells

27 Oct 2016

Abstract excerpt

BACKGROUND: During meiosis, the X and Y chromosomes are transcriptionally silenced. The persistence of repressive chromatin marks on the sex chromatin after meiosis initially led to the assumption that XY gene silencing persists to some extent in spermatids. Considering the many reports of XY-linked genes expressed and needed in the post-meiotic phase of mouse spermatogenesis, it is still unclear whether or not...

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Share to Chromosomal and Genetic Variations
Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 27795737
DOI: 10.1186/s13072-016-0099-8

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