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Article

Offspring production of ovarian organoids derived from spermatogonial stem cells by defined factors with chromatin reorganization

18 Mar 2021

Abstract excerpt

Introduction: Fate determination of germline stem cells remains poorly understood at the chromatin structure level. Objectives: Our research hopes to develop successful offspring production of ovarian organoids derived from spermatogonial stem cells (SSCs) by defined factors. Methods: The offspring production from oocytes transdifferentiated from mouse SSCs with tracking of transplanted SSCs in vivo, single cell...

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PMID: 34603780
DOI: 10.1016/j.jare.2021.03.006

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