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Article

IL-1β and IL-1ra are key regulators of the inflammatory response to RNA vaccines

2021-04-05

Abstract excerpt

<title>Abstract</title> <p>Excessive systemic inflammation is characteristic to various acute conditions including sepsis, viral infections and immunotherapy-induced adverse events such as cytokine release syndrome (CRS). Recently, several clinical trials evaluating variants of lipid-formulated RNA vaccines for either cancer or COVID-19 have reported systemic inflammatory responses that limit vaccine dosing in hu...

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Identifiers and source

Literature Corpus work
11131232-399e-5c8a-8960-8a30fdef7cea
DOI
10.21203/rs.3.rs-378991/v1
Open publication

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IL-1β and IL-1ra are key regulators of the inflammatory response to RNA vaccinesDOI 10.21203/rs.3.rs-378991/v1
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