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Article

Interleukin-1 and interleukin-1 antagonism

15 Apr 1991

Abstract excerpt

The polypeptide cytokine interleukin-1 (IL-1) affects nearly every tissue and organ system. IL-1 is the prototype of the pro-inflammatory cytokines in that it induces the expression of a variety of genes and the synthesis of several proteins that, in turn, induce acute and chronic inflammatory changes. IL-1 is also the prototypic "alarm" cytokine in that it brings about increases in a variety of defense...

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PMID: 1826616
DOI: 10.1182/blood.v77.8.1627.1627

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Source receipt: pubmed, retrieved 7 Sept 2026.

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