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Article

Interleukin-1 and interleukin-1 antagonism

1991-04-15

Abstract excerpt

The polypeptide cytokine interleukin-1 (IL-1) affects nearly every tissue and organ system. IL-1 is the prototype of the pro-inflammatory cytokines in that it induces the expression of a variety of genes and the synthesis of several proteins that, in turn, induce acute and chronic inflammatory changes. IL-1 is also the prototypic “alarm' cytokine in that it brings about increases in a variety of defense mechanisms...

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Literature Corpus work
19265e5d-835c-53f8-943b-c1bf91fb3c69
DOI
10.1182/blood.v77.8.1627.bloodjournal7781627
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Interleukin-1 and interleukin-1 antagonismDOI 10.1182/blood.v77.8.1627.bloodjournal7781627
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