Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeted lipid nanoparticles for RNA therapeutics and immunomodulation in leukocytes.

Advanced drug delivery reviews - 1 Jan 2020

Veiga Nuphar, Diesendruck Yael, Peer Dan

Abstract excerpt

Abnormalities in leukocytes' function are associated with many immune related disorders, such as cancer, autoimmunity and susceptibility to infectious diseases. Recent developments in Genome-wide-association-studies give rise to new opportunities for novel therapeutics. RNA-based modalities, that allow a selective genetic manipulation in vivo, are powerful tools for personalized medicine, enabling downregulation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Transfer Techniques
Share to Genetic Variation
Share to Immunomodulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukocytes

Share to Lipids

Share to Nanoparticles

Share to RNA, Small Interfering

Source

Identifiers

PMID: 32298783
DOI: 10.1016/j.addr.2020.04.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeted lipid nanoparticles for RNA therapeutics and immunomodulation in leukocytes.PMID 32298783Read ↗

Targeted delivery of RNA-based therapeutics enables functional analysis of macrophage subpopulationsSemantic proximity Read ↗

Lipid Nanoparticles for Spleen-Targeted RNA deliverySemantic proximity Read ↗

Lipid nanoparticles for delivery of RNA therapeutics: Current status and the role of in vivo imagingSemantic proximity Read ↗

Highly efficient CD4+ T cell targeting and genetic recombination using engineered CD4+ cell-homing mRNA-LNPsSemantic proximity Read ↗

Lipid nanoparticles allow efficient and harmless ex vivo gene editing of human hematopoietic cellsSemantic proximity Read ↗

RNA-loaded nanoparticles for the treatment of hematological cancersSemantic proximity Read ↗

Exploring precision treatments in immune‐mediated inflammatory diseases: Harnessing the infinite potential of nucleic acid deliverySemantic proximity Read ↗

Nanomedicine for Cancer and Autoimmune ImmunotherapySemantic proximity Read ↗

Exosomes: Potential Next-Generation Nanocarriers for the Therapy of Inflammatory DiseasesSemantic proximity Read ↗

Coordinated Tuning of Ionizable Lipids and Formulation Redirects mRNA Vaccines Toward Lymphoid-Specific CD4 <sup>+</sup> T Cell ImmunitySemantic proximity Read ↗

Enhanced epigenetic modulation via mRNA-encapsulated lipid nanoparticles enables targeted anti-inflammatory controlSemantic proximity Read ↗

Lipid Nanoparticle Delivery Systems to Enable mRNA-Based TherapeuticsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.