Article

Investigation of MDR1 Gene Polymorphism and Losartan Plasma Concentration in Patients Undergoing Hypertensive Episodes While under Losartan Treatment

2022-08-26

Abstract excerpt

<h4>Aim: </h4> Losartan, a drug in the angiotensin receptor blocker (ARB) family, is the substrate of the Multi Drug Resistance-1 (MDR1) drug-efflux protein encoded by the ABCB1 gene. This study seeks to investigate the MDR1 gene polymorphism and losartan concentration in order to identify drug resistance in patients presenting to the emergency department (ED) with a hypertensive episode while having losartan trea...

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Literature Corpus work: 10d098ec-3c74-5645-b642-a282441074dd
DOI: 10.22541/au.166152073.33966146/v1

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