Article
Association of angiotensin II type 1-receptor gene polymorphisms with the risk of developing hypertension in Mexican individuals.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Mar 2012
Martínez-Rodríguez Nancy, Posadas-Romero Carlos, Cardoso Guillermo, Pérez-Rodríguez José Manuel, Pérez-Hernández Nonanzit, Vallejo Maite, Vargas-Alarcón Gilberto
Abstract excerpt
INTRODUCTION: Hypertension is a complex disease in which a significant interaction between genetic and environmental factors takes place. The renin-angiotensin system plays an important role regulating blood pressure to maintain homeostasis and vascular tone. In the present work, the role of angiotensin II type 1-receptor (AGTR1) gene polymorphisms as susceptibility markers for hypertension was evaluated....
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