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Article

Renin angiotensin system blockage associates with insertion/deletion polymorphism of angiotensin-converting enzyme in patients with hypertensive emergency.

DNA and cell biology - 1 Sept 2013

Vilela-Martin José F, Vaz-de-Melo Renan O, Cosenso-Martin Luciana N, Kuniyoshi Cristina H, Yugar-Toledo Juan C, Pinhel Marcela A S, de Souza Gisele F, Souza Dorotéia R S, Pimenta Eduardo, Moreno Heitor, Cipullo José P

Abstract excerpt

Hypertensive crisis (HC) stands out as a form of acute elevation of blood pressure (BP). It can manifest itself as hypertensive emergency (HE) or hypertensive urgency (HU), which is usually accompanied with levels of diastolic BP ≥120 mmHg. Angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism may influence manifestations of HC. Thus, this study evaluated the influence of ACE I/D...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23869738
DOI: 10.1089/dna.2012.1951

Genes

ACE

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